Human Leukemia-Associated Anti-Nuclear Reactivity
نویسندگان
چکیده
منابع مشابه
Nonhuman primates express human leukemia-associated antigens.
Serologic studies using four murine monoclonal antibodies specific for the common acute lymphoblastic leukemia antigen (CALLA) and five monoclonal antibodies specific for the gp24 surface antigen indicate that these leukemia-associated antigens are present on cells of comparable tissues in man and in four nonhuman primates. As in man, adherent cell populations obtained from skin, lung, and bone...
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Acetylcholinesterase (AChE) is expressed in murine megakaryocytes (MK), where its antisense inhibition suppresses differentiation, yet was never detected in human MK. Here, we report that AChE is produced in normal human bone marrow MK and in cell lines derived thereof. Reverse transcriptase-polymerase chain reaction (RT-PCR) amplification showed two ACHEmRNA forms in human megakaryoblastic DAM...
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I . Rigby WFC, Ball ED, Guyre PM, Fanger MV: The effects of recombinant-DNA-derived interferons on the growth of myeloid progenitor cells. Blood 65:858, 1985 2. Taetle R, Buick RM, McCulloch EA: Effect of interferon in vitro on colony formation in culture by blast cell progenitors in acute myeloblastic leukemia. Blood 56:549, 1980 3. Greenberg PL, Mosney SA: Cytotoxic effects of interferon in v...
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To identify melanoma associated antigens (MAAs) shared by human and guinea pig melanoma cells, a battery of murine monoclonal antibodies (MoAbs) to human MAA and an antiserum to S100 protein were tested with four newly established guinea pig melanoma cell lines. Only the monoclonal antibodies 149.53 and 225.28 which recognize distinct determinants of the human high molecular weight-MAA (HMW-MAA...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1974
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.71.3.685